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Reaction of Aminomalononitrile and Benzylic Compounds as a Plausible Route to Phenylalanine

As a possible route to phenylalanine, reaction of aminomalononitrile with benzylic compounds was studied. 2-Benzyl-2-aminomalononitrile ( 3 ) was obtained in a good yield when aminomalononitrile p -toluenesulfonate ( 1 ) was treated with benzyl bromide ( 2 ) in THF using triethylamine as a base. The...

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Auteurs principaux: Chiaki Kuroda, Reiri Kobayashi, Saeka Kurebayashi, Kanako Tazawa, Arisa Masuda, Ryo Takeuchi, Ayako Washio, Hiroyuki Onuki
Format: Artigo
Langue:Inglês
Publié: SAGE Publishing 2020-01-01
Collection:Natural Product Communications
Accès en ligne:https://doi.org/10.1177/1934578X20901417
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