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Human dorsal forebrain organoids show differentiation-state-specific protein secretion

Summary: The human brain microenvironment undergoes dynamic changes during development, which have been incompletely characterized in in vitro models including neural organoids. Here, we used liquid chromatography-mass spectrometry to investigate proteome and secretome changes in human dorsal forebr...

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Bibliografiske detaljer
Principais autores: Zeynep Yentür, Theresa Kagermeier, Kseniia Sarieva, Mohamed A. Jarboui, Katharina Becker, Simone Mayer
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2025-07-01
Serier:iScience
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Online adgang:http://www.sciencedirect.com/science/article/pii/S2589004225011964
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