Culture-independent detection of Mycobacterium tuberculosis complex DNA using targeted next generation sequencing in African buffalo (Syncerus caffer) oronasal swabs in South Africa

African buffaloes (Syncerus caffer) are wildlife maintenance hosts of Mycobacterium bovis (M. bovis), the causative agent of animal tuberculosis (aTB) in multiple ecosystems across South Africa. In addition to their role as keystone species, these animals are vital to South Africa’s economy as a hig...

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Autores principales:	Sinegugu Kholeka Mhlophe, Charlene Clarke, Giovanni Ghielmetti, Megan Matthews, Tanya Jane Kerr, Michele Ann Miller, Wynand Johan Goosen
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2025-02-01
Colección:	Frontiers in Veterinary Science
Materias:	African buffaloes culture-independent detection Mycobacterium tuberculosis complex oronasal swabs Oxford Nanopore Technologies targeted next generation sequencing
Acceso en línea:	https://www.frontiersin.org/articles/10.3389/fvets.2025.1523628/full
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