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Subclinical Hypothyroidism Following Imatinib Use in Nigerian BCR::ABL1-positive Chronic Myeloid Leukemia Patients: A Prospective Cohort Study

Background: Thyroid toxicity has been reported with tyrosine kinase inhibitors (TKIs) such as sunitinib and sorafenib, targeting angiogenic tyrosine kinase receptors. However, the effect of imatinib, a first-line TKI for chronic myeloid leukemia (CML) patients on the thyroid, has been inconclusive....

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Principais autores: Ibrahim Oluwaseun Ahmed, Muritala Abiola Asafa, Babatunde Ayodeji Adeagbo, Tewogbade Adeoye Adedeji, Christianah Mopelola Asaleye, Rahman Ayodele Bolarinwa, Muheez Alani Durosinmi
Format: Artigo
Sprog:Inglês
Udgivet: Wolters Kluwer Medknow Publications 2024-09-01
Serier:Journal of Applied Hematology
Fag:
bcr::abl1
chronic myeloid leukemia
imatinib mesylate
subclinical hypothyroidism
Online adgang:https://journals.lww.com/10.4103/joah.joah_121_23
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