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TERT mutations-associated alterations in clinical characteristics, immune environment and therapy response in glioblastomas

Abstract Objective TERT is the most frequently mutated gene in adult glioblastomas (GBMs) defined by the 2021 World Health Organization classification system. The present study aims to explore differences in clinical characteristics and immune microenvironment between TERT mutant and wild-type GBM....

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Principais autores: Feng Tang, Xi Chen, Jin-Sheng Liu, Zhen-Yuan Liu, Jin-Zhou Yang, Ze-Fen Wang, Zhi-Qiang Li
Format: Artigo
Sprog:Inglês
Udgivet: Springer 2023-08-01
Serier:Discover Oncology
Fag:
TERT
Glioblastomas
Immune microenvironment
Immunotherapy
Online adgang:https://doi.org/10.1007/s12672-023-00760-w
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