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Alpha-particles induce autophagy in multiple myeloma cells

Objectives: Radiations emitted by the radionuclides in radioimmunotherapy (RIT) approaches induce direct killing of the targeted cells as well as indirect killing through bystander effect. Our research group is dedicated to the development of α-RIT, i.e RIT using α-particles especially for the treat...

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Principais autores: Joelle Marcelle Gaschet, Jean-Baptiste eGorin, Sébastien eGouard, Jérémie eMénager, Alfred eMorgenstern, Frank eBruchertseifer, Alain eFaivre-Chauvet, Yannick eGuilloux, Michel eChérel, François eDavodeau
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015-10-01
coleção:Frontiers in Medicine
Assuntos:
Autophagy
Multiple Myeloma
Radiobiology
Immunogenicity
Ionizing radiation
bismuth-213
Acesso em linha:http://journal.frontiersin.org/Journal/10.3389/fmed.2015.00074/full
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