Computer simulation of the spatial structure of MUC 1 peptides capable of inhibiting apoptosis

Identification of new effective inhibitors of apoptosis is an important task for drug development for treatment of a number diseases including neurogenerative diseases. Initiation of apoptosis occurs via the formationof macromolecular protein complexes. In these complexes, activation of key enzymes...

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Principais autores:	N. V. Ivanisenko, I. N. Lavrik, V. A. Ivanisenko
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders 2016-01-01
coleção:	Вавиловский журнал генетики и селекции
Assuntos:	apoptosis programmed cell death fa dd muc1 caspase-8 molecular dynamics implicit salvation generalized born model protein structure prediction
Acesso em linha:	https://vavilov.elpub.ru/jour/article/view/491
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