An improved LC-MS/MS method for the quantification of alverine and para hydroxy alverine in human plasma for a bioequivalence study☆

A highly sensitive and selective high performance liquid chromatography-tandem mass spectrometry method was developed and validated for the quantification of alverine (ALV) and its active metabolite, para hydroxy alverine (PHA), in human plasma. For sample preparation, solid phase extraction of anal...

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Principais autores:	Dhiraj M. Rathod, Keyur R. Patel, Hiren N. Mistri, Arvind G. Jangid, Pranav S. Shrivastav, Mallika Sanyal
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2017-04-01
coleção:	Journal of Pharmaceutical Analysis
Assuntos:	Alverine Para hydroxy alverine Liquid chromatography-tandem mass spectrometry Bioequivalence study Human plasma
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2095177916301228
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