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Hydroxysafflor Yellow A and Anhydrosafflor Yellow B Protect Against Cerebral Ischemia/Reperfusion Injury by Attenuating Oxidative Stress and Apoptosis via the Silent Information Regulator 1 Signaling Pathway

Hydroxysafflor yellow A (HSYA) and anhydrosafflor yellow B (AHSYB) are the main water-soluble compounds in Carthamus tinctorius L. However, studies on the effect of AHSYB on cerebral ischemia/reperfusion (I/R) injury and the therapeutic effect of HSYA by regulating silent information regulator 1 (SI...

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Principais autores: Yijia Fangma, Huifen Zhou, Chongyu Shao, Li Yu, Jiehong Yang, Haitong Wan, Yu He
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021-09-01
Serier:Frontiers in Pharmacology
Fag:
hydroxysafflor yellow A
anhydrosafflor yellow B
cerebral ischemia/reperfusion injury
oxidative stress
apoptosis
SIRT1 pathway
Online adgang:https://www.frontiersin.org/articles/10.3389/fphar.2021.739864/full
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