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TGIF2-mediated HMGB3 overexpression promotes esophageal squamous cell carcinoma proliferation and metastasis through TLR3/TGF-β signaling

Proliferation and metastasis are the core malignant characteristics in esophageal squamous cell carcinoma (ESCC) that contribute to poor prognosis. However, the mechanisms underlying cell proliferation and metastasis remain elusive. We explored the function of high-mobility group box (HMGB3) in prom...

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Main Authors: Liaoran Niu, Wanli Yang, Wei Zhou, Lili Duan, Qi Wang, Xiaoqian Wang, Yiding Li, Chengchao Xu, Yujie Zhang, Jinqiang Liu, Jian Zhang, Daiming Fan, Jianyong Zheng, Liu Hong
Format: Artigo
Language:Inglês
Published: KeAi Communications Co., Ltd. 2026-05-01
Series:Genes and Diseases
Subjects:
ESCC
HMGB3
Metastasis
Proliferation
TGIF2
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304225004763
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