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Dichloroacetate and Pyruvate Metabolism: Pyruvate Dehydrogenase Kinases as Targets Worth Investigating for Effective Therapy of Toxoplasmosis

Currently, the drugs used for toxoplasmosis have severe toxicity to human cells, and the treatment still lacks effective and safer alternatives. The search for novel drug targets is timely.

Uloženo v:
Hlavní autoři: Mariana Galvão Ferrarini, Lindice Mitie Nisimura, Richard Marcel Bruno Moreira Girard, Mayke Bezerra Alencar, Mariana Sayuri Ishikawa Fragoso, Carlla Assis Araújo-Silva, Alan de Almeida Veiga, Ana Paula Ressetti Abud, Sheila Cristina Nardelli, Rossiane C. Vommaro, Ariel Mariano Silber, Marie France-Sagot, Andréa Rodrigues Ávila
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2021-02-01
Edice:mSphere
On-line přístup:https://journals.asm.org/doi/10.1128/mSphere.01002-20
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