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Genes and pathways differentially expressed in the brains of Fxr2 knockout mice

Fragile X syndrome is a common inherited form of mental retardation and originates from the absence of expression of the FMR1 gene. This gene and its two homologues, FXR1 and FXR2, encode for a family of fragile X related (FXR) proteins with similar tissue distribution, together with sequence and fu...

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Principais autores: Sebastiano Cavallaro, Sabrina Paratore, Francesco Fradale, Femke M.S. de Vrij, Rob Willemsen, Ben A. Oostra
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2008-12-01
Serier:Neurobiology of Disease
Fag:
Fragile X syndrome
FXR1
FXR2
Genomics
Knockout
Mental retardation
Online adgang:http://www.sciencedirect.com/science/article/pii/S0969996108002155
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