Role of CXCL10 released from osteocytes in response to TNF-α stimulation on osteoclasts

Abstract Tumor necrosis factor-alpha (TNF-α) is a significant cytokine that regulates bone resorption under inflammatory conditions. However, its mechanism of action in osteocytes remains unclear. In this study, highly purified osteocytes were isolated from dentin matrix protein 1 (DMP1)-Topaz mice...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Mariko Miura, Hideki Kitaura, Fumitoshi Ohori, Kohei Narita, Jiayi Ren, Takahiro Noguchi, Aseel Marahleh, Jinghan Ma, Angyi Lin, Ziqiu Fan, Itaru Mizoguchi
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Nature Portfolio 2025-01-01
Σειρά:	Scientific Reports
Θέματα:	Osteocyte Osteoclast TNF-α CXCL10 Bone resorption Migration
Διαθέσιμο Online:	https://doi.org/10.1038/s41598-025-87092-7
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