Hypoxic glioma-derived exosomal miR-25-3p promotes macrophage M2 polarization by activating the PI3K-AKT-mTOR signaling pathway

Abstract Background Exosomes (EXO) play crucial roles in intercellular communication and glioma microenvironment modulation. Tumor-associated macrophages are more likely to become M2-like type macrophages in the immunosuppressive microenvironment. Here, we aimed to investigate the effects and molecu...

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Bibliografiske detaljer

Principais autores:	Zhiwei Xue, Junzhi Liu, Wenchen Xing, Feiyu Mu, Yanzhao Wu, Jiangli Zhao, Xuchen Liu, Donghai Wang, Jian Wang, Xingang Li, Jiwei Wang, Bin Huang
Format:	Artigo
Sprog:	Inglês
Udgivet:	BMC 2024-10-01
Serier:	Journal of Nanobiotechnology
Fag:	Glioma Exosomes miRNAs PHLPP2 AKT-mTOR
Online adgang:	https://doi.org/10.1186/s12951-024-02888-5
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