MODULATION OF THE CARDIAC SODIUM/BICARBONATE COTRANSPORTER BY THE RENIN ANGIOTENSIN ALDOSTERONE SYSTEM: PATHOPHYSIOLOGICAL CONSEQUENCES.

The sodium/bicarbonate cotransporter (NBC) is one of the major alkalinizing mechanisms in the cardiomyocytes. It has been demonstrated the existence of at least two functional isoforms, one that promotes the co-influx of 1 molecule of Na+ per 1 molecule of HCO3- (electroneutral isoform; NBCn1) and t...

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Principais autores:	Verónica Celeste De Giusti, María Carolina Ciancio, Alejandro eOrlowski, Ernesto Alejandro Aiello
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2014-01-01
Serija:	Frontiers in Physiology
Teme:	Aldosterone Angiotensin II Heart Hypertrophy sodium bicarbonate cotransporter
Online dostop:	http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00411/full
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