Novel Homo-SELEX for selecting universal aptamer for cross-species kidney injury biomarker KIM-1 in muti-scenario situ imaging

Abstract Kidney injury molecule 1 (KIM-1) has emerged as a critical biomarker for renal injury, playing a pivotal role in disease diagnosis and therapeutic monitoring. Despite its clinical importance, the development of high-affinity molecular probes for KIM-1 remains challenging. Aptamers are valua...

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Autori principali:	He Yang, Zaihui Du, Longjiao Zhu, Haiying Guo, Xu Che, Qiaona Cao, Yuyu Zhu, Xiaoyun He, Yulan Dong, Kunlun Huang, Wentao Xu
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2026-02-01
Serie:	Journal of Nanobiotechnology
Soggetti:	Homo-SELEX Universal aptamer KIM-1 Kidney injury In situ imaging
Accesso online:	https://doi.org/10.1186/s12951-026-04195-7
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