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Metformin inhibits spontaneous excitatory postsynaptic currents in spinal dorsal cord neurons from paclitaxel-treated rats

IntroductionCancer patients treated with paclitaxel often develop chemotherapy-induced peripheral neuropathy, which has not been effectively treated with drugs. The anti-diabetic drug metformin is effective in the treatment of neuropathic pain. The aim of this study was to elucidate effect of metfor...

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Autori principali: Ting-Ting Liu, Chun-Yu Qiu, Wang-Ping Hu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2023-05-01
Serie:Frontiers in Synaptic Neuroscience
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Accesso online:https://www.frontiersin.org/articles/10.3389/fnsyn.2023.1191383/full
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