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Antileishmanial and cytotoxic activity of dillapiole n-butyl ether

ABSTRACT Among the neglected diseases, American cutaneous leishmaniasis (ACL) still remains highly endemic in some tropical regions. The currently available drugs for treatment are highly toxic, prompting the search for new therapeutic options. The aim of this study was to evaluate the toxic potenti...

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Autors principals: Angela Maria Comapa BARROS, Ana Cristina da Silva PINTO, Fernanda Guilhon SIMPLICIO, Francisco Célio Maia CHAVES, Noam Gadelha da SILVA, Kelson Mota Teixeira de OLIVEIRA, Emersom Silva LIMA, Antonia Maria Ramos FRANCO
Format: Artigo
Idioma:Inglês
Publicat: Instituto Nacional de Pesquisas da Amazônia 2023-11-01
Col·lecció:Acta Amazonica
Matèries:
Leishmania
dillapiole analog
semi-synthesis
molecular modeling
Accés en línia:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672023000400285&lng=en&tlng=en
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