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Unraveling the mechanisms of benzimidazole resistance in hookworms: A molecular docking and dynamics study

Background: Benzimidazole resistance is an emerging challenge among parasitic helminths. It is caused by single nucleotide polymorphisms (SNPs) in specific loci in helminths’ β-tubulin genes. Field studies and laboratory investigations reported resistance-associated SNPs in 4 codon locations with 7...

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主要な著者: Jan Clyden B. Tenorio, Muhammad Fikri Heikal, Alok Kafle, Mark Andrian B. Macalalad, Fredmoore L. Orosco, Prasert Saichua, Sutas Suttiprapa
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2025-03-01
シリーズ:Journal of Genetic Engineering and Biotechnology
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オンライン・アクセス:http://www.sciencedirect.com/science/article/pii/S1687157X25000162
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