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Sex differences in mitochondrial gene expression during viral myocarditis

Abstract Background Myocarditis is an inflammation of the heart muscle most often caused by viral infections. Sex differences in the immune response during myocarditis have been well described but upstream mechanisms in the heart that might influence sex differences in disease are not completely und...

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Principais autores: Damian N. Di Florio, Gabriel J. Weigel, David J. Gorelov, Elizabeth J. McCabe, Danielle J. Beetler, Katie A. Shapiro, Katelyn A. Bruno, Isha Chekuri, Angita Jain, Emily R. Whelan, Gary R. Salomon, Sami Khatib, Natalie E. Bonvie-Hill, Jessica J. Fliess, Presley G. Giresi, Charwan Hamilton, Cameron J. Hartmoyer, Varsini Balamurugan, Ashley A. Darakjian, Brandy H. Edenfield, S. Christian Kocsis, Christopher J. McLeod, Leslie T. Cooper, Étienne Audet-Walsh, Michael J. Coronado, Jon Sin, DeLisa Fairweather
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2024-12-01
Series:Biology of Sex Differences
Assuntos:
Inflammation
Innate immunity
Coxsackievirus B3
Estrogen-related receptor alpha/ERRα
Mitochondria
Electron transport chain
Acceso en liña:https://doi.org/10.1186/s13293-024-00678-0
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