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HIV Infection Elicits Differential Transcriptomic Remodeling in CD4+ T Cells with Variable Proliferative Responses to the T Cell Receptor Stimulus

Identification of a cellular biomarker of latent HIV infection will facilitate the latent reservoir detection, quantification, and targeting for elimination. Unfortunately, the latency biomarkers reported in the literature define only a fraction of the entire reservoir. The latent HIV reservoir may...

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Principais autores: Xinlian Zhang, Savitha Deshmukh, Amey Mukim, Jasen Zhang, Nadejda Beliakova-Bethell
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-03-01
Serier:Pathogens
Fag:
HIV infection
response to T cell receptor stimulus
transcriptomic remodeling
single-cell RNA-Seq
biomarkers of HIV latency
Online adgang:https://www.mdpi.com/2076-0817/12/4/511
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