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Asymmetric one-pot sequential Friedel–Crafts-type alkylation and α-oxyamination catalyzed by a peptide and an enzyme

In the presence of a peptide catalyst and the oxidative enzyme laccase, a one-pot sequential reaction including a Friedel–Crafts-type alkylation of α,β-unsaturated aldehydes followed by an α-oxyamination was realized. The reaction in aqueous solvent to promote the enzymatic oxidation, and the use of...

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Autors principals: Kengo Akagawa, Ryota Umezawa, Kazuaki Kudo
Format: Artigo
Idioma:Inglês
Publicat: Beilstein-Institut 2012-08-01
Col·lecció:Beilstein Journal of Organic Chemistry
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Accés en línia:https://doi.org/10.3762/bjoc.8.152
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