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UQCRC1 engages cytochrome c for neuronal apoptotic cell death

Summary: Human ubiquinol-cytochrome c reductase core protein 1 (UQCRC1) is an evolutionarily conserved core subunit of mitochondrial respiratory chain complex III. We recently identified the disease-associated variants of UQCRC1 from patients with familial parkinsonism, but its function remains uncl...

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Hlavní autoři: Yu-Chien Hung, Kuan-Lin Huang, Po-Lin Chen, Jeng-Lin Li, Serena Huei-An Lu, Jui-Chih Chang, Han-Yi Lin, Wen-Chun Lo, Shu-Yi Huang, Tai-Ting Lee, Tai-Yi Lin, Yuzuru Imai, Nobutaka Hattori, Chin-San Liu, Su-Yi Tsai, Chun-Hong Chen, Chin-Hsien Lin, Chih-Chiang Chan
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2021-09-01
Edice:Cell Reports
Témata:
UQCRC1
mitochondrial respiratory chain
complex III
cytochrome c
apoptosis
Parkinson’s disease
On-line přístup:http://www.sciencedirect.com/science/article/pii/S2211124721011785
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