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Discovery and validation of Barrett's esophagus microRNA transcriptome by next generation sequencing.

Barrett's esophagus (BE) is transition from squamous to columnar mucosa as a result of gastroesophageal reflux disease (GERD). The role of microRNA during this transition has not been systematically studied.For initial screening, total RNA from 5 GERD and 6 BE patients was size fractionated. RNA <70...

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Hlavní autoři: Ajay Bansal, In-Hee Lee, Xiaoman Hong, Sharad C Mathur, Ossama Tawfik, Amit Rastogi, Navtej Buttar, Mahesh Visvanathan, Prateek Sharma, Lane K Christenson
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2013-01-01
Edice:PLoS ONE
On-line přístup:http://europepmc.org/articles/PMC3553128?pdf=render
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