PERIOD 2 regulates low-dose radioprotection via PER2/pGSK3β/β-catenin/Per2 loop

Summary: During evolution, humans are acclimatized to the stresses of natural radiation and circadian rhythmicity. Radiosensitivity of mammalian cells varies in the circadian period and adaptive radioprotection can be induced by pre-exposure to low-level radiation (LDR). It is unclear, however, if c...

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Dettagli Bibliografici

Autori principali:	Aris T. Alexandrou, Yixin Duan, Shanxiu Xu, Clifford Tepper, Ming Fan, Jason Tang, Jonathan Berg, Wassim Basheer, Tyler Valicenti, Paul F. Wilson, Matthew A. Coleman, Andrew T. Vaughan, Loning Fu, David J. Grdina, Jefferey Murley, Aijun Wang, Gayle Woloschak, Jian Jian Li
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2022-12-01
Serie:	iScience
Soggetti:	Biological sciences cell biology molecular biology
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2589004222018181
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