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Rapidly-manufactured CD276 CAR-T cells exhibit enhanced persistence and efficacy in pancreatic cancer

Abstract Background Pancreatic cancer is one of the most lethal malignancies and the lack of treatment options makes it more deadly. Chimeric Antigen Receptor T-cell (CAR-T) immunotherapy has revolutionized cancer treatment and made great breakthroughs in treating hematological malignancies, however...

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Auteurs principaux: Tian Deng, Yingzhi Deng, Shih-Ting Tsao, Qinghui Xiong, Yue Yao, Cuicui Liu, Ming yuan Gu, Fei Huang, Haiying Wang
Format: Artigo
Langue:Inglês
Publié: BMC 2024-07-01
Collection:Journal of Translational Medicine
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Accès en ligne:https://doi.org/10.1186/s12967-024-05462-7
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