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AZ 242, a novel PPARα/γ agonist with beneficial effects on insulin resistance and carbohydrate and lipid metabolism in ob/ob mice and obese Zucker rats

Abnormalities in fatty acid (333333333333382) metabolism underlie the development of insulin resistance and alterations in glucose metabolism, features characteristic of the metabolic syndrome and type 2 diabetes that can result in an increased risk of cardiovascular disease. We present pharmacodyna...

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Principais autores: Bengt Ljung, Krister Bamberg, Björn Dahllöf, Ann Kjellstedt, Nicholas D. Oakes, Jörgen Östling, Lennart Svensson, Germán Camejo
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2002-11-01
Serier:Journal of Lipid Research
Fag:
hypertriglyceridemia
peroxisome proliferator activated receptor
type 2 diabetes
Online adgang:http://www.sciencedirect.com/science/article/pii/S0022227520327607
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