Targeting dendritic cell-specific TNFR2 improves skin and joint inflammation in a murine model of psoriatic arthritis

Abstract Psoriasis (PsO) and Psoriatic arthritis (PsA) are TNF-alpha-dependent immune-mediated inflammatory diseases where dendritic cells (DC) play a critical role in disease pathogenesis. Although TNF-alpha receptor 2 (TNFR2) has been implicated in the pathology of psoriatic diseases, its specific...

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Detalhes bibliográficos

Principais autores:	Raminderjit Kaur, Jean Lin, Jennifer E. Harvey, Roberta Brambilla, Unnikrishnan M. Chandrasekharan, M. Elaine Husni
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2025-08-01
coleção:	Scientific Reports
Assuntos:	Dendritic cells TNFα receptor Psoriatic diseases
Acesso em linha:	https://doi.org/10.1038/s41598-025-15175-6
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