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F4, a collagen XIX-derived peptide, inhibits tumor angiogenesis through αvβ3 and α5β1 integrin interaction

We previously demonstrated that F4 peptide (CNPEDCLYPVSHAHQR) from collagen XIX was able to inhibit melanoma cell migrationin vitro and cancer progression in a mouse melanoma model. The aim of the present work was to study the anti-angiogenic properties of F4 peptide. We demonstrated that F4 peptide...

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Principais autores: Jean-Baptiste Oudart, Matthieu Villemin, Bertrand Brassart, Christèle Sellier, Christine Terryn, Aurélie Dupont-Deshorgue, Jean Claude Monboisse, François-Xavier Maquart, Laurent Ramont, Sylvie Brassart-Pasco
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis Group 2021-01-01
coleção:Cell Adhesion & Migration
Assuntos:
extracellular matrix
collagen xix
matrikine
integrin
angiogenesis
Acesso em linha:http://dx.doi.org/10.1080/19336918.2021.1951425
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