Apolipoprotein E4 interferes with lipid metabolism to exacerbate depression‐like behaviors in 5xFAD mice

Abstract Background Apolipoprotein E4 (ApoE4) allele is the strongest genetic risk factor for late‐onset Alzheimer's disease, and it can aggravate depressive symptoms in non‐AD patients. However, the impact of ApoE4 on AD‐associated depression‐like behaviors and its underlying pathogenic mechanisms...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Yanju Gong, Mingfeng Li, Min Liu, Xinghan Wu, Yanhong Li, Chuan Qin, Ling Zhang
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Wiley 2024-06-01
Цуврал:	Animal Models and Experimental Medicine
Нөхцлүүд:	5xFAD mice Alzheimer's disease ApoE4 allele depression like
Онлайн хандалт:	https://doi.org/10.1002/ame2.12446
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!