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Skin-Grafting and Dendritic Cell “Boosted” Humanized Mouse Models Allow the Pre-Clinical Evaluation of Therapeutic Cancer Vaccines

Vaccines have been hailed as one of the most remarkable medical advancements in human history, and their potential for treating cancer by generating or expanding anti-tumor T cells has garnered significant interest in recent years. However, the limited efficacy of therapeutic cancer vaccines in clin...

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Principais autores: Bijun Zeng, Davide Moi, Lynn Tolley, Natalie Molotkov, Ian Hector Frazer, Christopher Perry, Riccardo Dolcetti, Roberta Mazzieri, Jazmina L. G. Cruz
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2023-08-01
coleção:Cells
Assuntos:
cancer
vaccine
T cells
animal models
dendritic cells
humanized-mouse models
Acesso em linha:https://www.mdpi.com/2073-4409/12/16/2094
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