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An analysis toolbox to explore mesenchymal migration heterogeneity reveals adaptive switching between distinct modes

Mesenchymal (lamellipodial) migration is heterogeneous, although whether this reflects progressive variability or discrete, 'switchable' migration modalities, remains unclear. We present an analytical toolbox, based on quantitative single-cell imaging data, to interrogate this heterogeneity. Integra...

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Principais autores: Hamdah Shafqat-Abbasi, Jacob M Kowalewski, Alexa Kiss, Xiaowei Gong, Pablo Hernandez-Varas, Ulrich Berge, Mehrdad Jafari-Mamaghani, John G Lock, Staffan Strömblad
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications Ltd 2016-01-01
coleção:eLife
Assuntos:
cell motility
cell adhesion
membrane dynamics
plasticity
heterogeneity
systems microscopy
Acesso em linha:https://elifesciences.org/articles/11384
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