Exploring the Synthetic Chemistry of Phenyl-3-(5-aryl-2-furyl)- 2-propen-1-ones as Urease Inhibitors: Mechanistic Approach through Urease Inhibition, Molecular Docking and Structure–Activity Relationship

Furan chalcone scaffolds belong to the most privileged and promising oxygen-containing heterocyclic class of compounds, which have a wide spectrum of therapeutic applications in the field of pharmaceutics, pharmacology, and medicinal chemistry. This research described the synthesis of a series of tw...

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Autores principales:	Miraj Fatima, Samina Aslam, Ansa Madeeha Zafar, Ali Irfan, Misbahul Ain Khan, Muhammad Ashraf, Shah Faisal, Sobia Noreen, Gamal A. Shazly, Bakht Ramin Shah, Yousef A. Bin Jardan
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2023-08-01
Colección:	Biomedicines
Materias:	furan carbaldehyde Claisen–Schmidt condensation furan chalcones urease inhibition molecular docking SAR
Acceso en línea:	https://www.mdpi.com/2227-9059/11/9/2428
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