Actin crosslinker competition and sorting drive emergent GUV size-dependent actin network architecture

By encapsulating proteins in giant unilamellar vesicles, Bashirzadeh et al find that actin crosslinkers, α-actinin and fascin, can self-assemble with actin into complex structures that depend on the degree of confinement. Further analysis and modeling show that α-actinin and fascin sort to separate...

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Библиографические подробности

Главные авторы:	Yashar Bashirzadeh, Steven A. Redford, Chatipat Lorpaiboon, Alessandro Groaz, Hossein Moghimianavval, Thomas Litschel, Petra Schwille, Glen M. Hocky, Aaron R. Dinner, Allen P. Liu
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Nature Portfolio 2021-09-01
Серии:	Communications Biology
Online-ссылка:	https://doi.org/10.1038/s42003-021-02653-6
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