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The role of Notch ligand Jagged1 in osteosarcoma proliferation, metastasis, and recurrence

Abstract Background Osteosarcoma is the most common primary bone cancer occurring in young adults and the 5-year survival rate of patients with metastatic osteosarcoma is less than 30% due to high metastatic recurrence and drug resistance. Notch is a highly conserved cell to cell signaling pathway i...

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Bibliografiske detaljer
Principais autores: Jianping Zhang, Na Li, Siyu Lu, Yanling Chen, Lequn Shan, Xingcheng Zhao, Yongqing Xu
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2021-03-01
Serier:Journal of Orthopaedic Surgery and Research
Fag:
Online adgang:https://doi.org/10.1186/s13018-021-02372-y
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