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PfSPZ-CVac malaria vaccine demonstrates safety among malaria-experienced adults: A randomized, controlled phase 1 trial

Summary: Background: Plasmodium falciparum (Pf) Sporozoite (SPZ) Chemoprophylaxis Vaccine (PfSPZ-CVac) involves concurrently administering infectious PfSPZ and malaria drug, often chloroquine (CQ), to kill liver-emerging parasites. PfSPZ-CVac (CQ) protected 100% of malaria-naïve participants agains...

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Asıl Yazarlar: Drissa Coulibaly, Abdoulaye K. Kone, Karim Traore, Amadou Niangaly, Bourema Kouriba, Charles Arama, Amatigue Zeguime, Amagana Dolo, Kirsten E. Lyke, Christopher V. Plowe, Yonas Abebe, Gail E. Potter, Jessie K. Kennedy, Shirley M. Galbiati, Effie Nomicos, Gregory A. Deye, Thomas L. Richie, Eric R. James, Natasha KC, B. Kim Lee Sim, Stephen L. Hoffman, Ogobara K. Doumbo, Mahamadou A. Thera, Matthew B. Laurens
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2022-10-01
Seri Bilgileri:EClinicalMedicine
Konular:
Malaria vaccine
Plasmodium falciparum
Sporozoite
PfSPZ Vaccine
PfSPZ-CVac
Online Erişim:http://www.sciencedirect.com/science/article/pii/S2589537022003091
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