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Epigenetic Reelin Dysfunction in Schizophrenia and Related Neuropsychiatric Disorders

REELN (RELN) is a large (420 kDa) glycoprotein that in adulthood is mostly synthesized in GABAergic neurons of corticolimbic structures. Upon secretion in the extracellular matrix, RELN binds to VLDL, APOE2, and 32 Integrin receptors located on dendritic shafts and spines of postsynaptic pyramidal...

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書誌詳細
主要な著者: Alessandro eGuidotti, Dennis R Grayson, Hector M Caruncho
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2016-04-01
シリーズ:Frontiers in Cellular Neuroscience
主題:
オンライン・アクセス:http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00089/full
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