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Advanced glycation end-product crosslinking activates a type VI secretion system phospholipase effector protein

Abstract Advanced glycation end-products (AGE) are a pervasive form of protein damage implicated in the pathogenesis of neurodegenerative disease, atherosclerosis and diabetes mellitus. Glycation is typically mediated by reactive dicarbonyl compounds that accumulate in all cells as toxic byproducts...

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主要な著者: Steven J. Jensen, Bonnie J. Cuthbert, Fernando Garza-Sánchez, Colette C. Helou, Rodger de Miranda, Celia W. Goulding, Christopher S. Hayes
フォーマット: Artigo
言語:Inglês
出版事項: Nature Portfolio 2024-10-01
シリーズ:Nature Communications
オンライン・アクセス:https://doi.org/10.1038/s41467-024-53075-x
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