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NSUN7-mediated m5C methylation of NLRP3 promotes pyroptosis in ovarian granulosa cells in polycystic ovary syndrome

Abstract Pyroptosis is a pathogenenic mechanism of polycystic ovary syndrome (PCOS). N5-methylcytosine (m5C) methylation is a RNA modification that affects the progression of diseases. However, its role in PCOS remains not understood. This study aimed to investigate the role of NSUN7 in PCOS, partic...

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Detalhes bibliográficos
Principais autores: Guobin Xu, Junlong Wang, Na Gu, Tiansong Yang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2025-10-01
coleção:Scientific Reports
Assuntos:
Acesso em linha:https://doi.org/10.1038/s41598-025-19209-x
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