A 3D Organotypic Human Bronchial Model Reveals Persistent Infection and Modulated Inflammatory Response when Exposed to <i>Brucella abortus</i>

<i>Brucella</i> infection is frequently acquired by inhalation, but the pathogen disseminates systemically from the lungs. However, little is known about the interaction of <i>Brucella</i> spp. with the airways. Using a 3D air-exposed organotypic human bronchial tissue model (polarized 16HBE14o- bro...

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Bibliographic Details

Main Authors:	Iván Mathias Alonso Paiva, Florencia Muñoz González, Cecilia Rotondaro, Magali Bialer, Paula Arias, Arlinet Kierbel, Mariana C. Ferrero, Pablo C. Baldi
Format:	Artigo
Language:	Inglês
Published:	MDPI AG 2026-03-01
Series:	Tropical Medicine and Infectious Disease
Subjects:	<i>Brucella</i> bronchial 3D model bronchial epithelium lung fibroblasts cytokines immune cross-talk
Online Access:	https://www.mdpi.com/2414-6366/11/3/78
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