New Approaches for Basophil Activation Tests Employing Dendrimeric Antigen–Silica Nanoparticle Composites

In vitro cell activation through specific IgE bound to high-affinity receptors on the basophil surface is a widely used strategy for the evaluation of IgE-mediated immediate hypersensitivity reactions to betalactams. Cellular activation requires drug conjugation to a protein to form a large enough s...

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Detalhes bibliográficos

Principais autores:	Silvia Calvo-Serrano, Esther Matamoros, Jose Antonio Céspedes, Rubén Fernández-Santamaría, Violeta Gil-Ocaña, Ezequiel Perez-Inestrosa, Cecilia Frecha, Maria I. Montañez, Yolanda Vida, Cristobalina Mayorga, Maria J. Torres
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2024-08-01
coleção:	Pharmaceutics
Assuntos:	PAMAM dendrimers dendrimeric antigens silica nanoparticles drug allergy diagnosis basophil activation test
Acesso em linha:	https://www.mdpi.com/1999-4923/16/8/1039
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