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Assessing the feasibility of quantitative SPECT imaging for low 212Pb activity concentrations using anthropomorphic phantoms

Abstract Background Lead-212 (212Pb) is being investigated for alpha therapies, but it can be challenging to image. To investigate the quantitative accuracy of 212Pb SPECT images for patient geometries and low activity concentrations, we imaged an anthropomorphic phantom with 212Pb, and studied the...

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Main Authors: Johan Høiness, Caroline Stokke, Eivor Hernes, Lars Tore Gyland Mikalsen, Monika Kvassheim
Format: Artigo
Language:Inglês
Published: SpringerOpen 2026-01-01
Series:EJNMMI Physics
Subjects:
SPECT
212Pb
Phantom
Anthropomorphic
Quantitative
3D printing
Online Access:https://doi.org/10.1186/s40658-025-00829-1
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