Pharmacokinetic and pharmacodynamic integration and modeling of enrofloxacin in swine for Escherichia coli

The aim of this study was tooptimize the dose regimens of enrofloxacin to reduce the development of fluoroquinolone resistance in Escherichia coli (E.coli) using pharmacokinetic/pharmacodynamic (PK/PD) modeling approach. The single dose (2.5 mg/kg body weight) of enrofloxacin was administered intram...

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Principais autores:	Jianyi eWang, Dongmei eChen, Haihong eHao
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2016-02-01
Serija:	Frontiers in Microbiology
Teme:	Escherichia coli pig enrofloxacin pharmacokinetic PK/PD modeling Pharmacodynamic
Online dostop:	http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00036/full
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