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SNARE mimicry by the CD225 domain of IFITM3 enables regulation of homotypic late endosome fusion

Abstract The CD225/Dispanin superfamily contains membrane proteins that regulate vesicular transport and membrane fusion events required for neurotransmission, glucose transport, and antiviral immunity. However, how the CD225 domain controls membrane trafficking has remained unknown. Here we show th...

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Principais autores: Kazi Rahman, Isaiah Wilt, Abigail A Jolley, Bhabadeb Chowdhury, Siddhartha A K Datta, Alex A Compton
Format: Artigo
Jezik:Inglês
Izdano: Springer Nature 2024-12-01
Serija:The EMBO Journal
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Online dostop:https://doi.org/10.1038/s44318-024-00334-8
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