Role of Anterior Cingulate Cortex in Instrumental Learning: Blockade of Dopamine D1 Receptors Suppresses Overt but Not Covert Learning

HIGHLIGHTSBlockade of dopamine D1 receptors in ACC suppressed instrumental learning when overt responding was required.Covert learning through observation was not impaired.After treatment with a dopamine antagonist, instrumental learning recovered but not the rat's pretreatment level of effort toler...

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Principais autores:	Mayada Aly-Mahmoud, Pascal Carlier, Sherine A. Salam, Mariam Houari Selmani, Marie Z. Moftah, Monique Esclapez, Driss Boussaoud
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2017-05-01
coleção:	Frontiers in Behavioral Neuroscience
Assuntos:	associative learning medial prefrontal cortex effort tolerance rodent observational learning
Acesso em linha:	http://journal.frontiersin.org/article/10.3389/fnbeh.2017.00082/full
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