Mesoporous silica coated spicules for photodynamic therapy of metastatic melanoma

Abstract We report on the fabrication of mesoporous silicon dioxide coated Haliclona sp. spicules (mSHS) to enhance the delivery of the insoluble photosensitizer protoporphyrin IX (PpIX) into deep skin layers and mediate photodynamic therapy for metastatic melanoma in mice. The mSHS are dispersed sh...

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Huvudupphov:	Xuejiao Liang, Jialiang Zhang, Chi Zhang, Haojie Zhai, Ping Yang, Ming Chen
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	BMC 2024-04-01
Serie:	Journal of Nanobiotechnology
Ämnen:	SHS Mesoporous silica Melanoma Photodynamic therapy Skin delivery
Länkar:	https://doi.org/10.1186/s12951-024-02471-y
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