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Epigenetic alterations of 11beta-hydroxysteroid dehydrogenase 1 gene in the adipose tissue of patients with primary aldosteronism

11Beta-hydroxysteroid dehydrogenase 1 (11β-HSD1) is a key enzyme involved in metabolic syndrome. Transcript-specific epigenetic regulation of the gene encoding 11β-HSD1 (HSD11B1) has been reported. We examined the mRNA level and methylation status of the HSD11B1 promoter region in the adipose tissue...

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Principais autores: Yoshimichi Takeda, Masashi Demura, Mitsuhiro Kometani, Shigehiro Karashima, Daisuke Aono, Seigo Konishi, Shin-ichi Horike, Makiko Meguro-Horike, Takashi Yoneda, Yoshiyu Takeda
Formato: Artigo
Idioma:Inglês
Publicado em: The Japan Endocrine Society 2024-03-01
coleção:Endocrine Journal
Assuntos:
aldosterone
cortisol
11beta-hydroxysteroid dehydrogenase
adipose tissue
epigenetics
Acesso em linha:https://www.jstage.jst.go.jp/article/endocrj/71/3/71_EJ23-0103/_html/-char/en
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