Key Factor Study for Generic Long-Acting PLGA Microspheres Based on a Reverse Engineering of Vivitrol^®

The FDA (U.S. Food and Drug Administration) has approved only a negligible number of poly(lactide-co-glycolide) (PLGA)-based microsphere formulations, indicating the difficulty in developing a PLGA microsphere. A thorough understanding of microsphere formulations is essential to meet the challenge o...

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Autori principali:	Yabing Hua, Zengming Wang, Dan Wang, Xiaoming Lin, Boshi Liu, Hui Zhang, Jing Gao, Aiping Zheng
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2021-02-01
Serie:	Molecules
Soggetti:	PLGA microspheres reverse engineering Vivitrol<sup>®</sup> generic naltrexone-loaded microspheres critical process parameters
Accesso online:	https://www.mdpi.com/1420-3049/26/5/1247
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