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Tirzepatide modulates gut microbiota homeostasis to protect against diabetic kidney disease

PurposeThis study evaluated the effect of Tirzepatide on metabolic profiles, kidney function, and gut microbiota composition in mice with diabetic kidney disease (DKD) and clarify the relationship between gut microbiota alterations and the renoprotective effects.MethodsSeven-week-old diabetic db/db...

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Hoofdauteurs: Jun Ma, Mengyuan Tao, Wencheng Zhang, Li Zhou, Henglu Zhang, Fei Li, Hongman Zhang, Di Yao, Weiping Lu, Min Wang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2025-12-01
Reeks:Frontiers in Molecular Biosciences
Onderwerpen:
tirzepatide
GIP/GLP-1 RA
gut microbiota
diabetic kidney disease
glycaemic control
Online toegang:https://www.frontiersin.org/articles/10.3389/fmolb.2025.1715024/full
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