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Tenascin-C from the tissue microenvironment promotes muscle stem cell maintenance and function through Annexin A2

Abstract Skeletal muscle regeneration occurs through the finely timed activation of resident muscle stem cells (MuSC). Following injury, MuSC exit quiescence, undergo myogenic commitment, and regenerate the muscle. This process is coordinated by tissue microenvironment cues, however the underlying m...

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Bibliografiske detaljer
Principais autores: Alessandra Cecchini, Mafalda Loreti, Collin D. Kaufman, Cedomir Stamenkovic, Gabriele Guarnaccia, Alma Renero, Chiara Nicoletti, Anais Kervadec, Daphne Mayer, Shawn Delaware, Luca Caputo, Xiuqing Wei, Alexandre Colas, Pier Lorenzo Puri, Alessandra Sacco
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2025-12-01
Serier:Communications Biology
Online adgang:https://doi.org/10.1038/s42003-025-09189-z
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